10 Best CBD Oil of 2019: Reviews and Buying Guide

What exactly is Cannabidiol and what do you stand to gain from using it?

Cannabidiol(CBD) might just be the solution to many of your problems.

A solution that you probably never gave a second thought about.

It is safe and perfectly legal in all 50 states of the US, and if you’re not using it right now, you’re probably missing out on a health Revolution that is sweeping the nation.

But what solution can this so-called miraculous product provide?

Well, how about pain, anxiety, depression, sleep, for starters?

I’ve been using CBD oil extensively for quite some time now and can honestly say that EVERYONE needs to try it out.

And to make things easier, I’m here to teach you everything there is to know about this substance in order for you to make wiser choices.

So, don’t pull out your wallet just yet!

Read this guide first.

How I picked the best CBD oil

Working on this guide wasn’t really a piece of cake. I tried CBD oils from 20 different brands, scoured through the user reviews on Reddit, and visited other blogs for their opinion.

I even went ahead and asked 16,000 of my email subscribers to vote for their favorite brand before coming to a verdict. Close to 3000 people voted and now here I am with the results.

Please note that I am no way saying that all the products in my review are the best you’ll ever find. But the collective opinion of approximately 3000 people would say we’re pretty close.

It’s cool if you don’t agree with my choices. Different strokes for different folks, right?

But, let me just say that I take a look at lots of factors before passing judgment. And the thought that everyone wants the best value for their money never leave my mind.

Here are the factors I look into before rating a product:

  1. Potency: Cannabidiol needs to be potent and I test out everything that ranges from 100 mg to 4500 mg to see what works and what doesn’t.
  2. Price: Another huge factor that many CBD testers and reviewers overlook. I try to bring you only the products that offer excellent value for money.
  3. Ingredients: A bottle of CBD oil is only as good as the ingredients contained, so I test to ensure you’re getting the finest quality products that are free of harmful preservatives.
  4. Lab tests: I only recommend products that have been extensively lab tested for potency and purity. Lab tests are crucial when it comes to judging the authenticity.
  5. Hemp origin: The place/country from where the hemp is farmed has a tremendous impact on how the CBD oil tinctures turn out to be.
  6. Flavor: Though this is not very important to me, I do somewhat judge the products by how they taste. It doesn’t hurt, right? Plus, a lot of people consider this a deciding factor.
  7. Coupon codes: Ohh! I work hard to bring you some of the sweetest deals on the internet.
  8. CBD type: Just using CBD is not enough; I believe it’s crucial that you have an understanding of its types – full-spectrum, isolate, or broad spectrum. I’ll explain this later in a bit.
  9. Guarantee: Everybody has the right to get their money back, so I test all the “100% satisfaction or your money back guarantees” to see the companies are indeed telling the truth.
  10. Shipping time: I don’t like to buy from companies who take forever to ship their products. Pretty sure you don’t either.

Top 10 Best CBD Oils: Official Reviews

#1 Nuleaf Naturals Full-Spectrum CBD Oil

When it comes to manufacturing high-quality, full spectrum oils, Nuleaf Naturals is easily among the best.

They offer a wide variety of concentrations ranging from just 240 mg and going all the way up to a mammoth 4850 mg; all of which are available in the natural flavor.

  1. Potency: 240 mg to 4850 mg
  2. Price: $38.5 to $439
  3. Ingredients: USDA certified 100% organic cold-pressed hemp oil, full spectrum hemp extract
  4. Lab Tests: Conducted by a third-party lab, Steep Hill.
  5. Hemp Grown in: Licensed farms in Colorado, USA
  6. Flavor: Only available in the natural flavor
  7. Coupon Codes: CBDALL20 to get 20% OFF
  8. Type: Full Spectrum
  9. Guarantee: Full refund on receiving an incorrect or defective product
  10. Shipping Time: Products are shipped via USPS Priority Mail and usually take 2-3 business days for delivery

You can read the full Nuleaf Naturals Review

My Experience

Before I proceed with the review, I need to get something out of the way first. You see, this isn’t my first experience with the Nuleaf Naturals brand.

Their CBD oil is my go-to product for treating my chronic back pain and anything related to pain. And so, I’ll try to stay as unbiased as possible.

I purchased the 2425 mg CBD oil bottle for this review and took a week-long break from my existing CBD medications.

After my chronic back pain and anxiety conditions became unbearable, I took the first dose of the CBD oil. Within a few minutes, I felt much better. In fact, my back pain was almost gone and, Moreover, I had no problem sleeping that night.

Honestly, you just can’t fault Nuleaf Naturals’ quality. However, I just wish their products were a tad bit cheaper.

#2 Fab CBD Premium Drops

If you’re new to the world of CBD, this is one brand you must check out.

Why, you ask?

Well, this is one of the few CBD brands which offers their oil tinctures in 3 different flavors! And that includes a moderately high concentration oil of 1200 mg.

  1. Potency: 150 mg to 1200 mg
  2. Price: $39 to $129
  3. Ingredients: Hemp extract, MCT oil, natural flavors
  4. Lab Tests: Conducted by a third-party lab, ProVerde Laboratories.
  5. Hemp Grown in: Colorado, USA
  6. Flavor: Available in 3 flavors – natural, mint, and citrus.
  7. Coupon Codes: ALLCBD15 
  8. Type: Full Spectrum
  9. Guarantee: Full refund (minus shipping) in 30 days, if you’re unsatisfied with your purchase
  10. Shipping Time: Standard shipping in the US takes 5 – 7 business days. International shipping may be delayed due to customs and can take up to 4 weeks from purchase.

Read the Fab CBD Review before you decide to buy.

My Experience

Reviewing a FabCBD product brings back some good ol’ memories. When I started taking CBD oil on a regular basis, this was one of the very first brands I was loyal to.

Sure, things may have changed a lot since then, but, I still believe FabCBD is one of the best CBD brands for a beginner.

For this review, I purchased the 1200 mg oil tincture in the mint flavor. Even though I’ve become completely accustomed to the natural flavor, I do love the occasional flavored CBD products.

Just like before, I took a week-long break from my existing CBD medications until my chronic back pain and anxiety problems became unbearable.

After the first dose of the CBD oil, my back pain was almost gone. However, it didn’t quite have the same effect on my anxiety.

Thankfully, the second dose improved things further. And at this point, only traces of my anxiety remained. Needless to say, the third dose brought me back to my usual self.

All in all, Fab CBD is an excellent brand. However, it is let down by the lack of ultra-high concentration CBD oils.

#3 CBDistillery Full Spectrum Tincture

High on quality and extremely well priced; these two phrases can accurately sum up the CBDistillery brand.

They offer a variety of concentration options for their CBD oils, including a humongous 5000 mg product! Moreover, they offer their products in both full-spectrum and isolate forms.

  1. Potency: 150 mg to 5000 mg
  2. Price: $20 to $240
  3. Ingredients: Full Spectrum Oil – Coconut MCT oil and hemp oil extract; CBD Isolate Oil – MCT coconut oil and anhydrous hemp oil
  4. Lab Tests: Conducted by a third-party lab, ProVerde Laboratories. You can find the test results in the photos section of each product page.
  5. Hemp Grown in: Colorado, USA
  6. Flavor: Only available in the natural flavor.
  7. Coupon Codes: ALLCBD10, ALLCBD5
  8. Type: Full Spectrum and Isolate; both options are available.
  9. Guarantee: No money back guarantee
  10. Shipping Time: Standard shipping in the US takes 3 – 5 business days. You can also opt for USPS priority shipping, which will usually take 2 – 3 business days.

You should definitely read this CBDistillery review.

My Experience

I’ve always admired CBDistillery’s impressive pricing for their CBD oils. They produce their CBD in the US, which lets them cut some costs. Shipping 

Now, for this review, I was a little torn between selecting the full spectrum oil and the CBD isolate oil. In the end, I settled with a 2500 mg bottle of the full spectrum product.

I went through my usual routine and took a one-week break from my existing CBD medications. After the first dose of the oil, I felt significantly better. My chronic back pain was almost wiped out. And my anxiety too reduced a lot.

However, it still took me three doses to get back to my normal self.

All in all, this is a fantastic product, but, not quite on the level of the Nuleaf Naturals oil.  

#4 Hemp Bombs CBD Tincture                                                                                   

If you’re a fan of full-spectrum products, you might just have to skip this great brand. On the flip side, if you prefer to isolate oils, then Hemp Bombs is surely among the best.

Not only are their products top notch, and offer impressive value as well.

  1. Potency: 300 mg to 4000 mg
  2. Price: $50 to $300
  3. Ingredients: Hemp oil, grape seed oil, MCT oil
  4. Lab Tests: Conducted by a third-party lab, Desert Valley Testing. You can find the test results of all their products on this page.
  5. Hemp Grown in: Formerly grown in Europe. Now, they have shifted their farms to the US.
  6. Flavor: Watermelon and Peppermint.   
  7. Coupon Codes: ALLCBD15 
  8. Type: Isolate
  9. Guarantee: 30-Day Money Back Guarantee
  10. Shipping Time: It usually takes 5 – 10 business days to ship the product within the US. If you need your product early, Hemp Bombs also offers overnight and 2-Day shipping. For international orders, shipping time can range from 15 to 20 days.

People’s Experience

My dad once again volunteered to help me out. And this time around, I went ahead and purchased the 2000 mg CBD oil for him.

Just like before, he took a three-day break from his existing CBD medications. Once his pain became unbearable, he took the first dose of the CBD oil.

Soon after, his condition significantly improved, even more so than the CBDfx product. However, I believe it had more to do with the concentrated dose than the quality of the CBD oil itself.

After the second dose of the oil, only traces of his pain remained. Needless to say, the third dose got him back to his usual self.

In my opinion, Hemp Bombs surely makes one of the best isolate oils on the market. However, they are let down by the lack of full-spectrum oils.

Moreover, they do not offer their oils in the natural flavor. That’s a little absurd if you ask me.

#5 CBDPure Hemp Oil Extract

High-quality CBD oil? Check. Well-priced? Check. 90 Day Money Back Guarantee? Check.

Hence, it’s no surprise why CBDPure ranks among the top five brands in this list.

The company offers their oil tinctures in three different concentrations – 100 mg, 300 mg, and 600 mg. Unfortunately, they do not have any ultra-high concentration CBD oils.

  1. Potency: 100 mg to 600 mg
  2. Price: $30 to $80
  3. Ingredients: Pure hemp extract, MCT oil
  4. Lab Tests: Conducted by a third-party lab, ProVerde Laboratories. You can find the test results in each product page.
  5. Hemp Grown in: Colorado, USA
  6. Flavor: Only available in the natural flavor.  
  7. Coupon Codes:
  8. Type: Full Spectrum
  9. Guarantee: 90-Day Money Back Guarantee
  10. Shipping Time: CBDPure offers both USPS First Class Mail or USPS Priority. The shipping time can take anywhere between 1 – 3 weeks.

People’s Experience

Once again, my dear mother was kind enough to test CBDPure’s hemp oil. And this time, I went with the 600 mg bottle.

For this review, mum took a three-day break from her existing CBD medications until her arthritis pain became unbearable. After the first dose of the CBD oil, her conditions improved significantly, and she had no problem catching a full night’s sleep.

However, unlike in the case of Sol CBD’s oil, it took three doses of CBDPure’s hemp oil to get her back to her pain-free self.

If you ask me, I believe the brand has a lot of potential. However, it is let down by the lack of ultra-high concentration CBD oils.

And since their tinctures are only available in the natural flavor, it just doesn’t make it well-suited to beginners.

On the bright side, their excellent quality and 90 Day Money Back Guarantee are enough to redeem the shortcomings.

#6 CBDfx CBD Oil Tincture: 

If you’re looking for a high quality yet well priced full-spectrum CBD oil, then CBDfx should surely be on your radar.

The company manufactures their CBD products from hemp grown in their partner farms in Europe.

And as for concentration options, they offer three different variants for their tinctures – 500 mg, 1000 mg, and 1500 mg.

  1. Potency: 500 mg to 1500 mg
  2. Price: $75 to $160
  3. Ingredients: Hemp oil, MCT oil
  4. Lab Tests: Conducted by a third-party lab, SDPharmLabs. You can find the test results in each product page.
  5. Hemp Grown in: Partner farms in Europe
  6. Flavor: Only available in the natural flavor.
  7. Coupon Codes: ALLCBD15, RealCBD10
  8. Type: Full Spectrum
  9. Guarantee: No Money Back Guarantee
  10. Shipping Time: CBDfx offers free shipping in the US. Shipping time is 5 – 10 business days. They also offer international shipping. However, the shipping time differs from country to country.  

People’s Experience

After troubling my mom with two product reviews, I thought I should ask dad to test CBDfx’s oil tincture instead. The best part was that he was ready as ever to try out a new CBD product.

Now, before I proceed further, let me give you a brief overview of my dad’s condition. My father suffers from sciatica, and without his CBD medications, his pain can get quite frightening.

And just like in the case of my mom, I didn’t let dad go more than three days without his CBD. After the short break, he took the first dose of the 1500 mg oil. Soon after, he reported that he felt much better. Moreover, according to his fitness tracker, he was able to sleep for an additional two hours compared to the previous nights.

The second dose still wasn’t enough to remove all signs of his painful condition. Fortunately, the third dose got him back to his best.

All in all, CBDfx’s oil tinctures are great for the price. However, it still can’t quite match up to the quality provided by brands like Nuleaf Naturals.

#7 Sol CBD Tincture(High CBD) 

Like NuLeaf Naturals, Sol CBD is yet another company which manufactures CBD oils of the highest quality. Their tinctures are available in two concentrations – 300 mg and 3600 mg.

The smaller of the two is available in cinnamon and natural flavors, while the higher concentration product is only sold in the natural flavor.

  1. Potency: 300 mg to 3600 mg
  2. Price: $65 to $327
  3. Ingredients: Pure hemp extract, MCT oil
  4. Lab Tests: Conducted by a third-party lab, ProVerde Laboratories. You can find the test results in the photos section of each product page.
  5. Hemp Grown in: Northern Europe
  6. Flavor: 3600 mg bottle is only available in the natural flavor. 300 mg bottles are offered in Cinnamint and Natural flavors.
  7. Coupon Codes: ALLCBD7
  8. Type: Full Spectrum
  9. Guarantee: 60-Day Money Back Guarantee
  10. Shipping Time: Sol CBD offers both USPS First Class Mail or USPS Priority. You can expect your product to ship in 1-4 business days.

People’s Experience

As you might have guessed, reviewing CBD products can get quite strenuous for me. Fortunately, many of my family members and close friends also believe in the healing power of CBD.

So, this time around, my lovely mother decided to help me out with the Sol CBD 3600 mg review.

She suffers from arthritis in the knee and has successfully used CBD to keep her condition in check.

But, for her, even a couple of days without CBD can cause her pain to become unbearable. And so, after taking a short break from her existing CBD medications, she took the first dose of the tincture.

Within minutes, she felt much better, and only traces of her pain remained.

The second dose of the CBD oil got her back to her best.

In my opinion, Sol CBD’s excellent quality coupled with their 60 Day Moneyback Guarantee to make them a force to be reckoned. However, I hope they offer more concentration options for their oils.

#8 Endoca CBD Oil Drops

If you live outside the United States, you only have a handful of options when it comes to purchasing quality CBD products.

And Endoca is probably one of the most trustworthy international CBD brands out there.

The company offers two variants of their CBD oils – normal CBD Hemp Oil and Raw CBD Hemp Oil, which contains CBD along with CBDa. Both the variants are available in 300 mg and 1500 mg bottles

  1. Potency: 300 mg to 1500 mg
  2. Price: €26 to €129
  3. Ingredients: Hemp oil, grape seed oil, MCT oil
  4. Lab Tests: Conducted by Endoca. You can find the test results of all their batches on this page.
  5. Hemp Grown in: Mountains of Barcelona.
  6. Flavor: Only available in the natural flavor.  
  7. Coupon Codes: ALLCBD15, ALLCBD10 
  8. Type: Full Spectrum.
  9. Guarantee: No Money Back Guarantee
  10. Shipping Time: Standard shipping in the US takes 3 – 5 business days. If you need your product early, Endoca also offers overnight, 2-Day, and 3-Day shipping. For international customers, the product comes from the EU and is processed within 48 hours.

People’s Experience

Now I know I could have asked my dad to review this product as well. In fact, he was quite excited to try out Endoca’s CBD oil. However, I decided to shift the spotlight to my sister instead.

Unlike the rest of the family, my sister’s condition is a little less serious. You see, she has trouble sleeping. But, that is mainly because she’s up all night studying on her computer or tablet.

She normally doesn’t use CBD. But, she was ready to help me out anyway. So, for this review, I purchased the 300 mg bottle of Endoca’s normal CBD hemp oil.

After taking the standard dose of CBD oil, she slept for almost 6 hours according to her fitness tracker. Now, that might not seem like enough, but, it was still two hours more than her usual night’s sleep.

In my opinion, Endoca does sell high-quality oils, but, they are severely let down by the highly concentrated mixture of their 1500 mg oil.

That concentration comes in a tiny 10 ml bottle. And more often than not, it can lead to precious CBD getting wasted, especially if you mix it with your food.

#9 Bota Hemp

While Bota Hemp may not be as popular as some of the other brands featured before, that doesn’t mean they aren’t any good.

Sure, their CBD quality may not be on the level of top brands like Nuleaf Naturals, but, they redeem themselves by offering their oils at a great price. And they ship internationally too.

  1. Potency: 250 mg to 1000 mg
  2. Price: $40 to $100
  3. Ingredients: Hemp oil, MCT oil
  4. Lab Tests: Conducted by a third-party lab, Botanacor Services. You can find the test results in the photos section of each product page.  
  5. Hemp Grown in: Colorado, USA.
  6. Flavor: Only available in the natural flavor.  
  7. Coupon Codes: ALLCBD20
  8. Type: Full Spectrum
  9. Guarantee: No Money Back Guarantee
  10. Shipping Time: Ships internationally. Shipping time varies from country to country.  

People’s Experience

My sister was once again gracious enough to test out Bota Hemp’s CBD oil. This time around, she went on a seven-day break until her old 4-hour sleep schedule was restored.

After taking the first dose of the 500 mg oil, her sleep improved. 

It did not work as well as the #1 product on the list but,

Now, I understand that this is probably not the best and most accurate way to compare the two products; however, her sleep only gradually improved over the next few days despite her schedule remaining the same.

All things considered, I would rate this product above average. There are better products available in the same price range.

#10 Medix CBD Tinctures

If you’re looking for high-quality CBD isolate oils, then Medix CBD should surely be on your shortlist. They sell oil tinctures ranging from just 100 mg and going all the way up to a massive 4500 mg.

  1. Potency: 100 mg to 4500 mg
  2. Price: $27 to $450
  3. Ingredients: Hemp oil, Vitamin E
  4. Lab Tests: Conducted by a third-party lab, ProVerde Laboratories. You can find the test results in the respective product pages.
  5. Hemp Grown in: Kentucky, USA.
  6. Flavor: Only available in the natural flavor.  
  7. Coupon Codes: ALLCBD15
  8. Type: Isolate
  9. Guarantee: No Money Back Guarantee.
  10. Shipping Time: It usually takes 3 – 5 business days to ship the product within the US. However, for rural areas, it can take an additional 2 days.  

People’s Experience

For the last and final review, I didn’t take the help of my sister. Rather, I turned over to my friend, Kate, whom I met through an online CBD group.

Kate suffers from a severe case of fibromyalgia, and she has been successfully using CBD to treat her condition for the past few years.

And since she was looking to try out Medix CBD’s oil tinctures, I thought it would be the perfect time to ask for her help.

So, for this review, I got her the 1500 mg variant of the CBD oil. And after a seven-day break from my existing CBD medications, she took the first dose of the oil.

According to Kate, her condition improved quite a bit. However, it wasn’t as effective as her existing CBD product, which happens to be CBDistillery’s full spectrum oil.

In my opinion, the quality of the CBD oil doesn’t quite justify the price. However, if the company can reduce prices a tad bit and introduce flavored oils, they will surely climb up the rankings.

How to use CBD oil tinctures?

Using a CBD oil tincture is very easy! All you’ve got to do is take the required amount using the dropper and hold it under your tongue for 60 to 90 seconds before consuming.

A mistake I see people make often is that they confuse CBD tinctures and CBD vape oil. Though both are essentially oils, tinctures are NOT a concoction that can be used with a vaping device.

Tinctures, by very definition, mean you have to consume the substance sublingually and they come with a dropper attached.

I always recommend holding under the tongue for some time as it provides better bioavailability; meaning you’ll experience the effects of the product, faster.

Why you should not vape CBD oil?

Simply because vaping can make you inhale certain extraneous contaminants that can be harmful to the body. You also cannot count out that sticking to exact dosage is tough.

A lot of vape pen users have the notion that it is a much healthier option than consumption methods such as smoking.

While it is true to an extent, for example when you use e-liquids or vape oils from reputed companies, there are some things in the fine print.

What a lot of users fail to realize or don’t acknowledge that not every product out there is the same.

It’s incredibly crucial that you be careful in choosing the brands and cartridges to ensure you’re getting a product that’ effective and free of contaminants.

Still, there are some risks involved that I insist you learn about before vaping or trying out CBD in general:

  1. Excessive dosage

A quality CBD oil dosage is said to be four times as potent when it is vaped. And it’s natural that companies advertise this fact as an added advantage.

However, experts warn that it’s easy to indulge themselves unknowingly while vaping as opposed to consuming something by mouth.

So, unless you’re careful, you might end up with more CBD in your system, which in some circumstances can lead to adverse results.

If you decide to vape any CBD oil, please be careful about the dosage as you would be about any other substance.

  1. Ingesting heavy metals and other extraneous substances

The sole nature of vaping carries some risks even though the process might not.

A study conducted at the John Hopkins University found that vape pens, while they are being heated, release a significant amount of heavy metal like nickel and chromium, which the users eventually inhale.

These metal bits are released from the vape coils.

  1. Poor regulation

Vape oils have been on the news numerous times because of controversies. The 2017 study found that 7/10 products intentionally misrepresented CBD dosage and 2 others contained more than trace amounts of THC.

Occurrences like these are not uncommon and can more likely lead to disastrous effects through drug-drug interactions.

CBD Oil Dosage: How much CBD oil should you take?

This differs from person to person, but the general rule as I always say is start small and increase as you go.

As far as exact dosages are concerned, you have to take the following considerations into account:

  •    Your CBD concentration
  •    Your body weight
  •    Your body chemistry
  •    The condition you’re trying to treat

There is no such thing as “one size that fits all” in gauging the proper dosage. Consult your doctor for more advice.

7 Benefits of CBD Oil (Evidence-based)


We cannot talk about the benefits of CBD oil without discussing its effects on anxiety and its related disorders. While THC can act as a trigger for anxiousness, CBD is known to reduce the chances.

There have been numerous studies on the effects of cannabidiol on the human brain and researchers have found conclusive evidence of its benefits.

Thanks to the broad pharmacological profile of CBD, it interacts with several receptors that control our behavior related to fear and anxiety.

Cannabidiol works with a brain receptor called CB1, which are actually minute proteins that latch onto cells receiving chemical signals from various stimuli.

Even though we do not know to what extent CBD influences CB1, researchers have found that it alters serotonin signals, which is the hormone that makes us feel happy.

Lack of serotonin can not only lead to depression but can leave a long-term impact on mental health.

This human study from 2011 found that CBD indeed has beneficial effects on those having a social anxiety disorder. Participants took either a 400 mg oral dose of CBD or a placebo, and the ones who received CBD reported reduced levels of anxiety.

This study from Neurotherapeutics suggests that CBD exhibits numerous traits that can help manage anxiety and related symptoms that are panicolytic, anxiolytic, and anti-compulsive actions.

It also showed a marked decrease in fear and has the potential to reduce the long-term effects of stress that triggers anxiety.

Despite promising results, however, the researchers concluded by saying there have to be more studies done for further evidence.

Till now, it’s quite safe to say that the future looks bright for people suffering from conditions like social anxiety disorder, post-traumatic stress disorder (PTSD), general anxiety, and panic.


Pain is persistent, and most people who suffer from chronic pain know what it means to be on constant medication. Very few know or acknowledge the fact that CBD can act as a viable alternative.

CBD oil has shown good results in reducing pain, varying types of inflammation, and general discomfort that arises out of health conditions.

At this point in time, we can say that CBD oil and pain management can go hand-in-hand. This is good news, especially for those who are reliant on habit-forming medications.

Since researchers have solid evidence to believe cannabidiol influences our brain receptors and the immune system, it can create anti-inflammatory effects that can help manage pain.

And the best part? You don’t have to worry about side effects. This 2008 study concluded that CBD is indeed effective in managing pain without causing adverse side effects. It is also good for managing insomnia that accompanies pain.

A study done in 2016 observed the effects of CBD in rats having arthritis. Only by applying dosages of 0.6, 3.1, 6.2, and 62.3 mg per day, they were able to reduce inflammation on the rats’ joints with no side effects.

Note that CBD products aren’t approved as medication by the FDA. And more research is needed to say for absolute certain that cannabidiol can, in fact, treat pain for everyone.


According to the American Sleep Association, about 50 to 70 million adults in the US have some kind of sleep disorder. And that is just the tip of the iceberg!

Lack of sleep can affect everyone adversely and while over the counter medications are always available, use can quickly lead to abuse if one is not careful.

Since CBD has the ability to decrease anxiety levels, it can lead to better sleep at night or in general reduction in sleeping difficulties.

CBD oil, in small doses, is known to improve alertness and reduce the chances of experiencing daytime sleepiness, both of which are crucial for performance. It’s also crucial to maintain the proper sleep-wake cycle.

Research on rats has shown that CBD can help manage REM behavior disorder, a condition that makes people physically act out what they’re dreaming, which then results in disruption of sleeping pattern.

Cannabidiol is also showing promise in treating sleep apnea. Even though research on the direct correlation between CBD and sleep as been few and far between, we can look towards a good future.

Seizures and epilepsy:

CBD is showing great promise as a potential treatment for epilepsy. Even the FDA has approved use of CBD for treating two rare health conditions (Lennox-Gastaut syndrome and Dravet syndrome) characterized by intense epileptic seizures.

Epidiolex, which is a CBD oral solution, can be administered by doctors in the following circumstances:

  1. Lennox-Gastaut syndrome (LGS): a condition that occurs during childhood, between the ages of three and five years, and makes the child experience different types of seizures.
  2. Dravet syndrome (DS): a condition that is said to be mostly genetic and affects children under the age of five by giving them intense and frequent fever-related seizures.

These are the types of seizures that the FDA has concluded to be difficult to control with most kinds of medications.

The FDA has also set strict regulations and advised health care professionals not to prescribe Epidiolex to any child who’s less than 2 years of age.

This study published in 2017 tells that CBD is a better alternative to THC (tetrahydrocannabinol) as it showed the better result as an anticonvulsant in the animal test subject.

CBD is better not only because of enhanced effect in seizure disorders but also because of its non-psychoactive profile that does not carry the risk of developing habits.

As time passes, we can only expect the current stand of CBD being an excellent treatment for epilepsy and seizures to be solidified.


Researchers have reason to believe that cannabinoids have significant anti-cancer properties due to their antiemetic and analgesic nature.

This research published in 2012 suggests that CBD can control proliferation and survival of cancer cells by altering their signaling pathways.

This 2018 study further solidifies the previous findings of CBD’s anticarcinogenic properties.

The study also explains that cannabinoids do not affect CB receptors directly, but stimulates the production of reactive oxygen species that can kill the affected cancer cells.

Aside from direct treatment, CBD oil can also help manage pain and nausea of those going through chemotherapy better due to its relaxant properties.

Since cannabidiol has incredibly low levels of toxicity and is a non-psychoactive substance, researchers believe another breakthrough may come with further study.

Drug withdrawal:

Going through withdrawal is quite possibly one of the worst phases anyone can go through in their life. It is especially true in case of withdrawal from drugs.

Even milder forms of addictive substances like nicotine can have severe withdrawal effects, making the user feel anxious, nauseated, irritated, etc.

Even though cigarette smoking continues to be one of the greatest causes of death that can be preventable, quitting it, may be extremely tough.

The cognitive, physiological, and affective withdrawal symptoms show up within the first few days of nicotine deprivation.

Thankfully, this study published in the ‘Addictive Behaviors’ magazine found that cannabidiol can help reduce tobacco consumption.

The study observed that people who inhaled CBD had fewer cigarettes and did not experience extreme withdrawal symptoms that generally arise out of nicotine deprivation.

The Neurotherapeutics study claimed that cannabinoids derived from marijuana plants can have many other potential benefits, including helping people come out of opioid addiction.

The same researchers observed that CBD has mood uplifting properties and can ease symptoms related to substance abuse, including insomnia, anxiety, pain, etc.

It would be interesting to see what the future holds in store, given the fact that we have already seen such positive effect of CBD on drug withdrawal

Other neurological symptoms:

Additionally, CBD can help cope up with Depressionary bouts, panic attacks. CBD is also being tested for the treatment of schizophrenia

How does CBD work?

Cannabidiol (CBD) is a component of the cannabis plant, which is non-intoxicating, unlike THC. Since it is not psychoactive, you do not have to worry about getting high.

CBD works by influencing the endocannabinoid system of the human body, which has receptors spread out the whole of our body and brain.

The cannabinoid receptors (CB1 and CB2) are responsible for conducting multiple processes within our bodies such as regulating mood, pain sensation, appetite, and even memory.

CB1 receptors are mostly located in the central nervous system, with small amounts being in the kidney, liver, and lungs. CB2 receptors, on the other hand, are part of our immune system and found in the hematopoietic blood cells.

Though CBD does not directly stimulate the two receptors, it activates others like the adenosine, vanilloid, and serotonin.

When CBD activates the adesonine receptors, the effect becomes anti-inflammatory and anti-anxiety. It also releases glutamate and dopamine, two other crucial neurotransmitters that affect our mood and health.

CBD, when taken in high concentrations, have shown to influence the serotonin receptor 5-HT1A, which lead to antidepressant effects.

5-HT1A is the same receptor that influences a series of processes such as nausea, appetite, pain perception, anxiety, and sleep.

Last but not least, CBD works as a GPR55 blocker, thus reducing bone reabsorption and cancer cells from multiplying.

GPR55 is present inside our brain and is set to influence blood pressure level and bone density.

Even though we have a good understanding of how cannabidiol influences our body, it would still take time and research to unlock its true potential.

Know the difference between real CBD oil & hemp seed oil

If you’re someone who had never bought CBD before and were looking to buy, you’ve probably come across products marketed as hemp seed oil, or simply hemp oil.

Based on my experiences, I can tell you that many people think they’re both alike.

They’re not!

While hemp seed oil has its share of health benefits, it’s entirely different from what you get through CBD oil.

Here are the main differences:

  1. Source of the product

In most cases, CBD oil is derived from the strains of the hemp plant. Hemp seed oil, on the other hand, is extracted from the seed of the hemp plant.

And if it wasn’t obvious enough already, let me just say that the biochemical makeup of hemp plants and hemp seeds are completely different.

So, you’ll be in for a big disappointment if you believe hemp oil if the answer to anxiety, pain, depression, insomnia, etc.

  1. The difference in biochemical composition

To put it simply – hemp plant contains CBD; hemp seeds do not.

It’s close to impossible to formulate the same amount of therapeutic benefits as one would get out of CBD, from hemp seeds.

In addition, the Full-spectrum variety of CBD oil contains many beneficial compounds such as CBC, CBN, Terpenoids, and Flavonoids.

  1. Different effects

We’ve spoken at length about the beneficial aspects of CBD, but to recap we can say that the substance influences your endocannabinoid system. Thus, it helps  you with numerous conditions such as:

  •    Anxiety
  •    Pain
  •    Insomnia
  •    Depression
  •    Inflammation
  •    Withdrawal from drugs

We can go over the benefits of hemp seed oil as well, but what’s the point? CBD oil is far superior in every aspect anyway.

Can CBD oil make you high?

Technically, yes, but the chances are very slim if you buy CBD oil from top brands. How? That’s because top companies ensure their products contain trace or no amount of THC.

Most of the products sold online have less than 0.3% THC or no THC at all, and so the likelihood of anyone getting high is quite unrealistic.

How do you make sure you’re on the safe side?

Let’s start by learning the difference between these three CBD varieties:

  1. Full-spectrum

Full-spectrum CBD oil refers to products that not only contains CBD, but other cannabinoids such as CBN, CBG, and some terpenes.

They may even contain trace amounts of THC. Even though the THC level in most popular CBD oils is less than 0.3%, you can never rule out the chances of testing positive in a drug test.

  1. Isolate

CBD isolate, as the name implies, are products that have nothing but CBD in them. These products are marketed as 99% + pure CBD and are ideal for those who are sensitive to cannabinoids such as THC.

  1. Broad-spectrum

Broad-spectrum CBD oils are those with a limited cannabinoid profile. The term broad-spectrum is often used to denote products from which THC has been completely removed.

These offer most of the entourage benefits of full-spectrum CBD without any of the THC content.

But, is CBD oil legal?

Yes, CBD oil derived from the hemp plant is legal in all 50 states of the US if it does not contain illegal amounts of THC.

However, you have to keep in mind that though CBD is deemed to be safe for consumption, it is not without any side effects.

Some CBD oil Side Effects are:

  • Lightheadedness
  • Low blood pressure
  • Drowsiness
  • Dry mouth
  • Chances of increased tremor in Parkinson’s disease
  • Interactions with other drugs

Now, this is one crucial aspect everybody who wants to take CBD should bear in mind. CBD can and does interact with pharmaceutical drugs, so I highly recommend you consult a qualified medical professional before starting your dosage.

Since many drugs are metabolized by our liver (more specifically, the P-450 enzyme), CBD carries the risk of an adverse interaction.

Cannabidiol tends to maximize the utility of the P-450 complex enzyme power that is present in our liver, leaving less scope for proper metabolism of the ingested drug.

CBD and Drug Interaction:

Some common types of drugs that may trigger an adverse interaction are the following:

  •    Steroids
  •    HIV anti-virals
  •    Benzodiazepines
  •    Antihistamines
  •    Macrolide antibiotics
  •    Fentanyl
  •    Calcium channel blockers
  •    Macrolide antibiotics

You can read more here.

What should you expect Out of CBD Oil?

Look, let me be perfectly honest – things are often not as good as some people make them be.

You might have heard that CBD is the ultimate cure for every problem in life and thought that it’s BS. You’re right!

CBD is not the perfect cure and neither is it meant for everyone. But what I can say from years of experience is that it can help you live a better life.

Again, consult a doctor before taking CBD. You’d be doing yourself a huge favor.

Conclusion: what’s the Best CBD Oil

And that’s about all I have to say on the topic of Best CBD oils. Putting together such an extensive guide was not easy, but it was such a soul-satisfying experience!

I hope you learned some new things in this guide. If you have any questions, feel free to leave them as comments below.

I hope I left you better than when I found you.